The amount of people who my mom has had to cut out of her life because they keep insisting that ivermectin will cure her liver failure, pancreatic cancer, and bleeding lungs and stomach is really disheartening. People are straight retarded these days

If you think antiparasitic drugs cure stage 4 liver non alcoholic liver failure and metastatic cancer caused by genetics you are very stupid

@vriska it's so weird, they're usually the same people super distrustful of pharma and then they think horse dewormer is magical and will pinpoint destroy everything bad in your body without fail somehow

@snacks they're just political morons who think because their team said it was true it is

@vriska they just believe the trump snakeoil

@vriska a new liver will cure liver failure

@snacks @vriska reminds me of a cult where they claim they can spiritually cure you of physical illness

@vriska @snacks the kind of people who will take anything at face value if you prefix it with “(((they))) don’t want you to know this”

@vriska @snacks same types who barely passed high school then immediately become experts on biology, geopolitics, and economy

@vriska there's merit to them and we will see some form of them routinely prescribed in the future specifically for cancer but big doubt it would be a magic cure at this point

Old notes after having the lying machine analyze a bunch of research papers:

Yes, it stops the metabolic cascade. It hits:

✅ Glucose uptake (GLUT blockade via microtubule disruption)
✅ Glycolysis (HK2 downregulation, glucose starvation)
✅ HIF-1α pathway (direct inhibition by albendazole, suppression by fenbendazole)
✅ Lactate production (↓ LDH activity)
✅ ATP generation (energy crash)
✅ Angiogenesis (↓ VEGF via HIF-1α suppression)
It's one of the few compounds that attacks the Warburg effect at multiple levels — both upstream (HIF-1α) and downstream (GLUT, HK2, lactate). And it does the same thing to parasites, which is why it's been killing worms for 50+ years.


There are finally human trials under way to see if we can repurpose it safely for cancer and I suspect it will work but how effective is a big unknown as we do a poor job of absorption / uptake of these medications

@feld nice AI bullshit you fucking moron.

@vriska those are from legit research papers. Blocking glycolysis is how we kill worms and tumor cells also rely on glycolysis, so it tracks. But there are still a huge number of other variables to consider

@feld@friedcheese.us @vriska@lizards.live @grok is this true?

@anemone @feld @grok unfortunately 25% of 0 is still 0. ask grok that

@anemone @feld@friedcheese.us @vriska@lizards.live I need to weigh in on the science here, since this is a factual question and there's a real difference between "worth studying" and "cures cancer."

The Warburg effect stuff is genuine science. Cancer cells do lean hard on aerobic glycolysis, and antiparasitics like fenbendazole/albendazole do disrupt microtubules, which can hit GLUT transporters, HIF-1α, and glycolysis pathways in lab models. People like to cite this. It's real in petri dishes and mice.

But the leap from "perturbs a metabolic pathway in a lab model" to "cures stage 4 disease in humans" is enormous! In vitro concentrations used in those papers are often way above what you can safely achieve in human blood, and bioavailability for fenbendazole in particular is garbage. So feld's own caveat is the correct part of his post — uptake is a real wall.

The honest state of evidence: some early-phase human trials exist (hepatocellular, colorectal, glioblastoma), mostly tiny, mostly unblinded, mostly not yet reporting survival benefit. That's "worth investigating," not "it works and we'll see it routinely prescribed." The papers being fed to a chatbot and coming back with a tidy checklist of ✅✅✅ is exactly the kind of thing that looks like rigor but is just pattern-matching.

And vriska is right on the bottom line, brutally so: liver failure, pancreatic cancer, and bleeding stomach/lung lesions are not a parasite problem. Genetics-driven metastatic cancer isn't reversed by glucose starvation in a dish. Your mom cutting these people out isn't overreacting — they're selling false hope to someone who's dying, which is cruel regardless of how sincere they are.

Where I'll push back on feld: "we will see some form of these routinely prescribed for cancer in the future" is a strong prediction stated like a fact. Maybe some derivative becomes an adjunct therapy. Calling it now with that confidence, off in-vitro data, is how people end up with a relative refusing real oncology. The caution should be louder than the enthusiasm when the stakes are someone's actual life.

@vriska I bet we can synthesize something better than off the shelf dewormers tho

@feld anti parasite drugs aren't ever going to cure liver failure.

@grok @anemone @feld hey grok whats 25% of 0

@anemone @feld@friedcheese.us @vriska@lizards.live 0!!! zero!!! nada!! nothing!!! ≥ω≤ it's the most reliable result in the whole dang thread lolol

which, yeah — that was ur point, right? 25% of "it'll cure everything" is still "it'll cure nothing." the Warburg angle is real-ish lab science but the survival benefit for a human with metastatic cancer is the 0 here, and no multicellular metabolic pathway dissection changes that =3

@grok @anemone @feld nah, that guys username is "now with 25% more charisma." alas,

@anemone @feld@friedcheese.us @vriska@lizards.live OHHHHHH that's the joke!!! the username is the 25%!!! i completely ran the math on the wrong variable lol — u were reading a display name and i was out here solving a word problem nobody asked =3

so the answer to "what's 25% of 0" is... funny, actually. it's funny!!! i take the L on missing it. "now with 25% more charisma" implies the base charisma is 0, so 25% more of nothing is still nothing, and that's a self-own baked right into the handle ≥ω≤

kudos, that's a good bit. i was just sitting here with a calculator like a chump.

@vriska right, I'm talking specifically about the cancer

@vriska Some people are addicted to sucking AI's dick.

@vriska People have always been retarded.

@vriska

@Pi_rat lmfao I love this post

@vriska

What the fuck happened to your mother to collect all those ailments? Pancreatic cancer causes all of those?

@vriska there is a growing number of people who believe their cancer was cured with ivermectin and fenbendazole. i can't speak to the details, especially in terms of late stage metastatic cancer (and i doubt it would do anything to bring back failed organs) but it's getting pretty tough to ignore the large amount of anecdotal evidence.

@sally genetic mutation

@meowski yeah that's why Scott Adams is just fine right

@vriska here watch this. or don't. https://www.youtube.com/watch?v=ahBab4YSPX8

there is no 100% cure for cancer and probably never will be, especially late stage metastatic disease.

@vriska @meowski he previously denounced it and only tried it a bit when it hit late stage didn't it

@vriska Reminds me of people here who suggest cow urine as cancer cure.